development and validation of high performance liquid chromatography for determination of nystatin in pharmaceutical formulations

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A Novel High Performance Liquid Chromatographic Method for Determination of Nystatin in Pharmaceutical Formulations by Box–Behnken Statistical Experiment Design

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A Novel High Performance Liquid Chromatographic Method for Determination of Nystatin in Pharmaceutical Formulations by Box–Behnken Statistical Experiment Design

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a novel high performance liquid chromatographic method for determination of nystatin in pharmaceutical formulations by box–behnken statistical experiment design

this study a novel high performance liquid chromatography for the assay of nystatin in oral and vaginal tablets were optimized and validated using box–behnken experimental design. the method was performed in the isocratic mode on a rp-18 column (30 °c) using a mobile phase consisting of 0.05 m ammonium acetate buffer/ methanol mixture (30:70) and a flow-rate of 1.0 ml/min. the method was valida...

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Journal title:
research in pharmaceutical sciences

جلد ۷، شماره ۵، صفحات ۰-۰

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